Mycophenolate mofetil alleviates persistent proteinuria in IgA nephropathy
نویسندگان
چکیده
منابع مشابه
Mycophenolate mofetil treatment for IgA nephropathy: a meta-analysis.
BACKGROUND Worldwide, IgA nephropathy (IgAN) is the most common type of glomerulonephritis. Mycophenolate mofetil (MMF) is relatively selective for lymphocytes and inhibits antibody production by B cells more than other immunosuppressants. Several randomized controlled trials (RCTs) have analyzed the role of MMF in patients with IgAN. We conducted this meta-analysis of all available RCTs to asc...
متن کاملReduction of proteinuria with mycophenolate mofetil in predominantly membranous lupus nephropathy.
INTRODUCTION Lupus membranous nephropathy (LMN) presents a difficult clinical problem as no particular treatment has been proven to be effective. Studies have shown good results with mycophenolate mofetil (MMF) in proliferative lupus nephropathy (LN) (WHO class III and IV disease). OBJECTIVES To study whether MMF treatment was effective in membranous predominant LN in patients resistant to or...
متن کاملEfficacy and safety of mycophenolate mofetil treatment in IgA nephropathy: a systematic review
BACKGROUND IgA nephropathy is the most common primary glomerular disease worldwide and also the most frequent cause of kidney failure. Mycophenolate mofetil (MMF) is a selective immunosuppressant widely used in many autoimmune diseases. However, the benefits and risks of MMF for the treatment of IgA nephropathy remain uncertain. METHODS A systematic review and meta-analysis of randomized cont...
متن کاملMycophenolate mofetil in the treatment of IgA nephropathy: a systematic review.
INTRODUCTION The aim of this study was to determine the effectiveness of mycophenolate mofetil (MMF) in IgA nephropathy (IgAN). METHODS A search through Cochrane Library, EMBASE and PubMed was carried out. Randomised controlled trials (RCTs), which compared MMF with conventional treatments, were identified. Patients' baseline, treatment strategies and study end-points were compared. RESULTS...
متن کاملA randomized controlled trial of mycophenolate mofetil in patients with IgA nephropathy [ISRCTN62574616]
BACKGROUND IgAN is the most common type of glomerulonephritis in the world. Between 15 and 40 percent of adults and children diagnosed with IgAN eventually progress to ESRD. Despite the need for effective treatment strategies, very few RCTs for IgAN have been performed. The most effective therapies for IgAN appear to be corticosteroids, ACEi, and FOS that contain a high concentration of omega 3...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2005
ISSN: 0085-2538
DOI: 10.1111/j.1523-1755.2005.00460.x